ReMox III Spray (3-5% Minoxidil + 0.025% Tretinoin + 1.5% Azeleic Acid)

As you probably are aware, many doctors advise their hair loss patients to use a topical combination of minoxidil (the active ingredient in Rogaine) and tretinoin (also known as Retin-A). Numerous studies done over the last 10-15 years show that Retin-A alone can help promote hair growth to a minor degree. Furthermore, since we know tretinoin increases percutaneous absorption, it is widely accepted that combining tretinoin with minoxidil will allow for enhanced absorption of minoxidil and better results.

Azelaic Acid is a natural acid found in certain cereals, rye and animal products. It is FDA approved for the treatment of acne. Azelaic Acid is a very weak acid (weaker then vinegar). However, scientific research has shown that even very low concentrations Azelaic Acid inhibit 90% of DHT formation in vitro (see synopsis) The mechanism of action is 90% inhibition of 5 alpha reductase activity; 5-AR is the enzyme that converts human serum to testosterone, to DHT, which is the compound thought to be responsible for damaging hair follicles and an important factor in hair loss.

The new formulation contains Dimethyl Isorbide (DMI) as a solvent and penetrant, therefore allowing the Re-Mox sprays to be virtually free of Propylene Glycol. The new Re-Mox formula will not cause scalp irritation or dryness. The DMI increases absorption of all active ingredients through the scalp and into the hair follicle. DMI is a solvent compound that has been extensively researched and has been "Shown to enhance penetration of the active ingredients through the upper level scalp epidermis. It does not however, promote penetration of the ingredients into the bloodstream, therefore DMI produces a much lower incidence of skin irritation." The new formulation with DMI and Tretinoine increases the penetration of the active ingredients making Our Re-Mox Sprays Even more effective than they were before.